It is being over-prescribed in the US
RT @EricTopol: High level Paxlovid resistance (up to 80-fold) can be created in lab w/ high🦠fitness
2 reports replicate (mutations L50F, E166V/A, +/- L167F)
https://www.biorxiv.org/content/10.1101/2022.06.06.494921v1
https://www.biorxiv.org/content/10.1101/2022.06.07.495116v1
Supports need for genomic surveillance + development of more potent oral anti-viral pills

🐦🔗: https://nitter.eu/NChildersMEP/status/1534451042062151682